产品货号:
Z32792
中文名称:
ATG5抗体
英文名称:
Anti-ATG5 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATG5 Antibody |
指标别名 | APG5;APG5 LIKE;APG5L;Apoptosis specific protein;ASP;ATG5;Autophagy protein 5;hAPG5 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF,IP |
基因名称 | ATG5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human ATG5 |
实际分子量 | 55KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene.It is also known as APG5 or ASP,and this gene is mapped to 6q21.It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation.These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size.ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation.It is activated by ATG7 and forms a complex with ATG12 and ATG16L1.This complex is necessary for LC3-1 conjugation to PE to form LC3-II. |
Uniprot ID | Q9H1Y0 |
基因名全称 | Autophagy protein 5 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Immunocoprecipitation 1:20 |
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